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Home Poland Lesser Poland Katedra Farmakologii Uniwersytet Jagielloński Collegium Medicum

Katedra Farmakologii Uniwersytet Jagielloński Collegium Medicum

Grzegórzecka 16, 33-332 Kraków, Poland
+48 12 421 11 68
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Leszek Drabik (08/07/2020)
Research plans in the Department: -Research pathways of angiotensin I metabolism in animal models of cardiovascular diseases -Pathological glycation of proteins in diabetes -Effects of beta-blockers on the endothelium - mechanisms and importance in the pharmacotherapy of heart failure and atherosclerosis -Research of the mechanisms of endothelial dysfunction of coronary and peripheral vessels in heart failure in Tgαq transgenic mice * 44 -The therapeutic potential of nicotinamide derivatives in the light depends on the chemical structure of their action on the vascular endothelium -Flavonoids and endothelial dysfunction -Testing the anti-atherosclerotic potential of drugs on a unique experimental model of atherosclerosis - apoE / LDLR mice - double knockout -Testing the anti-atherosclerotic potential of drugs on the latest experimental model of atherosclerosis - apoE & eNOS mice - double knockout -Genetic polymorphisms of the NADPH oxidase - p22phox subunits (CYBA gene) -Estimation of the modulating effect of polyphenols on the parameters of oxidative stress in human blood vessels
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