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That's why some people stay slim whatever they eat  Gentside 2019/01/30 14:48 To follow An injustice, a difference of treatment simply unbearable ... and incomprehensible! While some struggle desperately to lose their extra pounds, others, intolerable privileged, can afford to eat without counting. A mysterious (and annoying) metabolic aberration, which researchers have finally discovered a part of the origins: as revealed in their publication published in the journal PLOS Genetics. As might be expected, the reasons for this surprising propensity for thinness are partially genetic: overweight people would benefit from the lack of a small group of genes related to obesity. "This work shows for the first time that thin people in good health are in general because they have a lower burden of genes that increase the risk that an individual is overweight," said in a statement one members of the research team, Sadaf Farooqi, from the University of Cambridge, UK. A study of magnitude To reach this conclusion, the scientists compared the genetic inheritance of a large cohort: more than 1,600 thin persons, nearly 2,000 suffering from obesity, and some 10,400 persons of a weight considered normal, the control group . At the same time, the study participants had to complete a questionnaire about their lifestyle and eating habits. The scientists were able to calculate the "genetic risk score" of each participant. As a result, obese people have been shown to be far more at risk - genetically speaking - than their counterparts of normal weight or slim weight gain. Unfair rules "The dice of genetics are staggered against [obese people]," says another member of the scientific team, Inês Barroso, of the Wellcome Sanger Institute. Far from claiming that the genome is the only one responsible for the injustice of thinness, the researchers are keen to clear obese people of the charges they are sometimes wrongly accused of. "[Thin people are not] because they are morally superior, as some people like to insinuate.It's easy to make a hasty judgment and criticize people for their weight, but science shows that things are much more complex, we have less of a hold on our weight than we would like to think, "said Sadaf Farooqi, whose discoveries seem to offer new hope for all those who struggle against excess weight. Solutions in sight "If we can discover the genes that prevent [thin people] from gaining weight, we may be able to target these genes to find new strategies for weight loss and help people who do not have this benefit," concludes the scientist. What finally tip the scales ... That of our bathrooms, but also, that of metabolic justice! See the original article